Table 1.
Characteristics of DM and non-DM groups.
| Characteristics | DM (n = 84) | Non-DM (n = 472) | p value |
|---|---|---|---|
| Age at HNC diagnosis (mean ± SD), years | 56.2 ± 11.2 | 52.0 ± 9.5 | <0.001 |
| Male, n (%) | 79 (94.0%) | 441 (93.4%) | 0.83 |
| Body weight prior CCRT (mean ± SD), kg | 62.2 ± 14.2 | 62.3 ± 12.6 | 0.61 |
| Tumor stage, n (%) | 0.66 | ||
| I/II | 4 (4.8%) | 24 (5.1%) | |
| III | 17 (20.2%) | 70 (14.8%) | |
| IVA | 48 (57.1%) | 295 (62.5%) | |
| IVB | 15 (17.9%) | 83 (17.6%) | |
| T classification, n (%) | 0.05 | ||
| T1/T2 | 29 (34.9%) | 156 (33.1%) | |
| T3 | 23 (27.7%) | 82 (17.4%) | |
| T4 | 31 (37.3%) | 233 (49.5%) | |
| N classification, n (%) | 0.05 | ||
| N0 | 15 (17.9%) | 99 (21.0%) | |
| N1 | 22 (26.2%) | 67 (14.2%) | |
| N2 | 42 (50.0%) | 270 (57.2%) | |
| N3 | 5 (6.0%) | 36 (7.6%) | |
| Tumor site, n (%) | 0.06 | ||
| Oral cavity | 41 (48.8%) | 175 (37.1%) | |
| Oropharnyx | 18 (21.4%) | 156 (33.0%) | |
| Hypopharnyx | 25 (29.8%) | 141 (29.9%) | |
| Treatment | 0.13 | ||
| Primary CCRT | 59 (70.2%) | 367 (77.8%) | |
| Adjuvant CCRT | 25 (29.8%) | 105 (22.2%) | |
| Exposure to smoking, n (%) | 69 (82.1%) | 398 (84.3%) | 0.62 |
| Exposure to alcohol, n (%) | 56 (66.7%) | 295 (62.5) | 0.47 |
| Exposure to betel quid, n (%) | 53 (63.1%) | 305 (64.6%) | 0.79 |
Abbreviations: CCRT = concurrent chemoradiotherapy; DM = diabetes mellitus; HNC = head and neck cancer; SD = standard deviation.