Table 2.

Senescence marker genes. SASP, senescence-associated secretory phenotype

Gene category	Number of genes	Genes
Senescence core genes	10	Cdkn2a, Bmi1, Trp53, Hmga1, Chek1, Chek2, Prodh, Tnfrsf10b, Cdkn1a, Dao
Senescence effector genes	9	Ppp1ca, Ahcy, Brf1, Map 2 k3, Map 2 k6, Smurf2, Tgfb1i1, Srsf1, Angptl2
SASP genes	44	Ccl2, Ccl24, Ccl3, Ccl5, Ctnnb1, Cxcl1, Cxcl10, Cxcl12, Cxcl2, Cxcl16, Hgf, Hmgb1, Icam1, Igfbp2, Igfbp3, Igfbp4, Igfbp5, Igfbp6, Igfbp7, Il15, Il18, Il1a, Il1b, Il2, Il6, Mif, Mmp12, Mmp13, Mmp14, Pgf, Plat, Timp2, Serpine1, Ccl3, Ccl4, Ang, Csf2, Kitl, Serpine2, Tnfrsf1a, Hgf, Nrg1, Ereg, Areg