Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 17;18(2):219–228. doi: 10.5217/ir.2019.00037

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Copyright 2020. Korean Association for the Study of Intestinal Diseases. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 3. — PAI-1 inhibitor (TM5275) suppressed intestinal fibrosis in TNBS-induced murine colitis. (A) Representative histological examples of each group (H&E and Masson trichrome staining). (B, C) Analysis of macroscopic score and microscopic score. (D) Collagen deposition was determined by the Sircol collagen assay. (E) Body weight changes of each group. (F) Colon length of each group. (G) Local production of MMP-9 in the colonic mucosa of chronic colitis by ELISA. Bars represent the median. P-value by two-way ANOVA with Bonferroni post-hoc test. ^a P<0.05; ^b P<0.001. PAI-1, plasminogen activator inhibitor-1; TNBS, 2,4,6-trinitrobenzene sulfonic acid; MMP-9, matrix metalloproteinase 9; ETOH, ethanol; CMC, carboxymethyl cellulose.