Table 2.
Group | Macroscopic score of colonic fibrosis |
|||||
---|---|---|---|---|---|---|
Adhesion | Thickness | Strictures | Dilation | Mucosal edema | Total macroscopic score | |
Ethanol (n = 10) | 0.20 ± 0.42 | 0.10 ± 0.32 | 0 | 0.20 ± 0.42 | 0.50 ± 0.42 | 1.00 ± 0.67 |
CMC (n = 10) | 0.90 ± 0.31 | 1.80 ± 0.42 | 1.80 ± 0.47 | 0.80 ± 0.42 | 0.80 ± 0.42 | 6.10 ± 0.87 |
TM5275 10 mg/kg (n = 9) | 0.74 ± 0.44 | 1.38 ± 0.72 | 1.65 ± 0.44 | 0.74 ± 0.50 | 0.74 ± 0.44 | 5.40 ± 0.60 |
TM5275 50 mg/kg (n = 10) | 0.80 ± 0.42 | 0.70 ± 0.67a,c | 0.80 ± 0.63a,c | 0.30 ± 0.48a,b | 0.50 ± 0.53a,b | 3.10 ± 0.73a,c |
Values are presented as mean±SD.
Statistical analyses were performed using two-way ANOVA with Bonferroni post-hoc test, which were compared with those of carboxymethyl cellulose (CMC) group.
P<0.05.
P<0.001.