Table 5.
Item | CL1) | HME1) (ppm) | P-ZnO1) | SEM | Contrasts2) (p-value) | |||||
---|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||
500 | 1,000 | 2,500 | CL vs others | HME vs P-ZnO | L | Q | ||||
Phase I (d 14) | ||||||||||
Feed (mg/kg DM) | 179 | 721 | 1,219 | 2,688 | 2,694 | - | - | - | - | - |
Feces (μg/g) | 1,068 | 4,297 | 6,936 | 13,659 | 17,364 | 173 | <0.001 | <0.001 | <0.001 | <0.001 |
Zn digestibility | 28.1 | 29.2 | 34.2 | 41.6 | 19.0 | 2.7 | 0.181 | <0.001 | <0.001 | 0.521 |
Serum (μg/mL) | 1.58 | 2.58 | 2.72 | 2.79 | 2.74 | 0.1 | <0.001 | 0.734 | <0.001 | <0.001 |
Phase II (d 28) | ||||||||||
Feed (mg/kg DM) | 204 | 730 | 1,211 | 2,628 | 2,699 | - | - | - | - | - |
Feces (μg/g) | 1,172 | 4,101 | 7,060 | 12,866 | 17,020 | 121 | <0.001 | <0.001 | <0.001 | <0.001 |
Zn digestibility | 32.1 | 34.2 | 30.6 | 44.2 | 20.1 | 2.9 | 0.465 | <0.001 | <0.001 | 0.479 |
Serum (μg/mL) | 1.91 | 3.07 | 2.85 | 3.66 | 3.04 | 0.11 | <0.001 | 0.249 | <0.001 | 0.169 |
HME, hot melt extrusion; SEM, standard error of means; DM, dry matter.
CL, basal diet without ZnO; HME, basal diet with 500, 1,000, and 2,500 ppm Zn as HME-ZnO; P-ZnO, basal diet with 2,500 ppm Zn as ZnO.
Linear (L) and quadratic (Q) effects of HME concentrations.