Fig. 1.

Feasibility of time-restricted feeding. a Compared with normal feeding (NF, black bars), all subjects successfully reduced their feeding window to within the allowed feeding duration (red lines) during time-restricted feeding (TRF, gray bars) resulting in b a reduction in the average daily feeding window. c Subjects were able to maintain a reduction in their daily feeding period throughout the 6-week TRF period with d good overall adherence. There were no adverse changes in e overall diet quality as assessed by the healthy eating index, f energy intake, g estimated energy expenditure, or h body mass. N = 22. Boxes represent median and interquartile range with 95% confidence intervals as whiskers. *p < 0.05. See also Supplementary Table 1, Supplementary Table 2, Supplementary Table 3, and Supplementary Table 4