Table 10.
Efficacy results of phase 3 IMbrave150 study: OS and PFS [modified from 47]
Co-primary endpoints | Atezo + Beva (n = 336) | Sorafenib (n = 165) |
---|---|---|
OS | ||
Median, months | NE | 13.2 (10.4 to NE) |
Hazard ratio | 0.58 (0.42–0.79) | |
p value | 0.0006 | |
PFS | ||
Median, months | 6.8 (5.7–8.3) | 4.3 (4.0–5.6) |
Hazard ratio | 0.59 (0.47–0.76) | |
p value | <0.0001 |
Median duration of follow-up: 8.6 months. Figures in parentheses are 95% CI. OS, overall survival; PFS, progression-free survival; Atezo, atezolizumab; Beva, bevacizumab; NE, not estimable.