Table 1.
Demographic and histological characteristics of the subjects participating in the study
| Variable | Primary and metastatic CRC | Nonneoplastic inflamed colon mucosa | Total | p value |
|---|---|---|---|---|
| Subjects | 113 (50.7%) | 110 (49.3%) | 223 | − |
| Age group | ||||
| ≤50 years | 97 (85.8%) | 49 (44.5%) | 146 | <0.001 |
| >50 years | 16 (14.2%) | 61 (55.5%) | 77 | |
| Gender | ||||
| Male | 60 (53.1%) | 54 (49.1%) | 114 | 0.593 |
| Female | 53 (46.9%) | 56 (50.9%) | 109 | |
| Mean age (range), years | 61.5±12 (28–90) | 47.8±16 (17–87) | 54.6±16 (17–90) | <0.001 |
| Smoking status | ||||
| Smoker | 26 (23.0%) | 34 (30.9%) | 60 | 0.184 |
| Nonsmoker | 87 (77.0%) | 76 (69.1%) | 163 | |
| Alcohol use | ||||
| Yes | 13 (11.5%) | 12 (10.9%) | 25 | 0.888 |
| No | 100 (88.5%) | 98 (89.1%) | 198 | |
| Family history of CRC | ||||
| Yes | 48 (42.5%) | 50 (45.5%) | 98 | 0.645 |
| No | 65 (57.5%) | 60 (54.5%) | 125 | |
| Histological differentiation | ||||
| Well differentiated | 94 (89.5%) | − | − | − |
| Moderately differentiated | 7 (6.7%) | − | − | − |
| Poorly differentiated | 4 (3.8%) | − | − | − |
Bold type denotes significance. CRC, colorectal cancer.