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. 2020 May 1;11:530. doi: 10.3389/fphar.2020.00530

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Copyright © 2020 Xiao, Liang, Ge, Qiu, Wan, Wu, Fei, Peng and Zeng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Si-Wei-Qing-Gan-Tang (SWQGT) on the levels of MEK/ERK, TAK1/p38 MAPK, and PI3K/Akt pathway related proteins. (A) Western blot; (B) p-MEK1/2 protein levels; (C) p-ERK1/2 protein levels; (D) PI3K protein levels (E) p-AKT protein levels; (F) p-p38 MAPK protein levels; E TLR4 protein levels. Methionine and choline-sufficient (MCS) group: MCS diet-fed rats, methionine and choline deficient (MCD) group: MCD diet-fed rats, SW-L group: rats fed with low dose of SWQGT and MCD diet, SW-H group: rats fed with high dose of SWQGT and MCD diet. The data are presented as the mean ± SD. ^#p < 0.05, ^###p < 0.001 vs. MCS group, ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs. MCD group.