Table 1.
Age-adjusted demographics of study participants by cohort in 1994 for NHS, 1999 for NHSII, and 1990 for HPFS
| NHS (n = 114,419) | NHSII (n = 115,813) | HPFS (n = 50,223) | ||||
|---|---|---|---|---|---|---|
| Incident glioma cases (n = 208) | Overall cohort | Incident glioma cases (n = 84) | Overall cohort | Incident glioma cases (n = 191) | Overall cohort | |
| Age, years (mean ± SD) | 62.4 (6.7) | 60.7 (7.2) | 46.3 (4.7) | 44.7 (4.7) | 59.4 (8.9) | 58.4 (9.8) |
| BMI, kg/m2 (mean ± SD) | 26.5 (3.9) | 26.5 (5.2) | 26.1 (2.6) | 26.6 (6.3) | 26.3 (3.0) | 25.7 (3.4) |
| Smoking status (%) | ||||||
| Never smoker | 46 | 43 | 66 | 64 | 46 | 45 |
| Former smoker | 45 | 40 | 26 | 25 | 41 | 40 |
| Current smoker | 9 | 13 | 6 | 9 | 6 | 8 |
| Unknown | 0 | 4 | 2 | 1 | 7 | 7 |
| Diagnosed hypertension (%) | 29 | 23 | 12 | 9 | 19 | 19 |
| Diagnosed hyperlipidemia (%) | 30 | 28 | 5 | 12 | 21 | 21 |
| Diagnosed diabetes (%) | 5 | 4 | 0 | 2 | 1 | 3 |
| Current statin users (%) | 7 | 7 | 2 | 3 | 3 | 3 |
All values apart from age are age-adjusted to the distribution of the cohort. The calendar years were the starting points for follow-up in these analyses
BMI body mass index; HPFS health professionals follow up study; NHS nurses’ health study; NHSII nurses’ health study II; SD standard deviation