Fig. 2.

Itemization of the GO: Biological Processes that were statistically enriched when comparing RML-infected mice to Uninfected mice by RNA-seq at 80, 100, and ~ 157 dpi. Few GO biological categories were affected at 80 dpi, but evidence of dysregulation in more biological processes was apparent as prion disease progressed. The affected categories are indicated with the number of genes that were differential expressed that are associated with that specific biological process in parentheses. Not all enriched biological processes could be included for 100 dpi and ~ 157 dpi but can be found in Additional File, Supplementary Dataset 3, where a full analysis of GO: Biological Processes, Cellular Component, and Molecular Function and the associated genes can be found