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. 2020 May 1;11:582. doi: 10.3389/fphar.2020.00582

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Copyright © 2020 Liu, Huang, Zhang, Mei and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of ICQA on the hepatic expression of HMGB1 and its cytoplasmic translocation in CCl₄-treated rats. (A) fluorescence staining of HMGB1 in the liver (scale bar = 50 μm); (B) fluorescence intensity; (C, D) nuclear and cytoplasmic expressions of HMGB1 in rat liver determined by Western blots. Data were expressed as mean ± SD, ^***P < 0.001 vs. control group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. model group.