Table 2.

TOP 15 up- and downregulated DEGs in the vaccinated groups. RNA-encoding DEGs and DEGs connected to the neuroendocrine-immune system are bolded and underlined, respectively

Ross[2x]		WL[2x]		Rosa[2x]		Rosa[1x]
Up-regulated
Gene Symbol	FC	Gene Symbol	FC.	Gene Symbol	FC	Gene Symbol	FC
GAL7	14,7	SNORD35	2,03	MX1	2,50	SNORA56	3,05
GAL1	9,4	GRM8	2,02	GVIN1	2,30	MHC region	2,88
GAL2	9,1	USP6NL	2,00	ISG12–2	2,23	U11	2,68
GAL6	8,3	MGST2	1,84	MHC	2,01	MIR1743	2,51
LECT2	6,8	MHC class I	1,80	ncRNA	2,01	–	2,32
GVIN1	6,3	gga-mir-147	1,76	ncRNA	2,01	MIR1596	1,96
TCRDV	4,9	OAT	1,69	ncRNA	2,01	C9ORF58	1,96
6TBGa-2	3,4	SLC2A9	1,68	ncRNA	2,01	MIR7B	1,93
SERPINB10	3,1	C2H6ORF105	1,53	LAMA1	1,93	SNORA66	1,89
LOC100858620	2,9	BORCS5	1,50	ZP1	1,83	SNORA23	1,87
RHCE	2,8	NONGGAT007307	1,50	TSPO2	1,82	MIR1680	1,87
S100A9	2,6	NADB-LER2	1,49	LAG3	1,77	SNORD90	1,87
ACKR2	2,5	STAM2	1,47	ARHGEF39	1,73	RPL23	1,84
SNORD24	2,4	TIFA	1,42	CCR8	1,72	SNORD14	1,82
TIMMDC1	2,3	CCLi9 gene	1,42	LYGL	1,72	ND4L	1,81
Down-regulated
DDX60	-2,9	IGLV	−5,12	–	−3,77	PRED.: LOC107050276	−4,28
DDX60	−2,9	GDPD2	−1,85	–	−2,07	CIAO1	−2,98
snoRNA GGN47	−2,9	LRRC4C	−1,77	GIMAP7L5	−2,00	SLC8A3	−2,25
NTMT1	−2,8	SNORA56	−1,65	IL28RA	−1,97	PRED.: MICA	−2,21
EYA1	−2,7	IFNA	−1,58	MIR1637	−1,82	PRED.: CYP2J2L2	− 1,97
RRBP1	−2,4	MIR1636	−1,55	TDRD5	−1,64	CHIR-B5	−1,79
GPR158	−2,2	AICDA	−1,53	GRTP1	−1,60	LOC431321	−1,78
LRRC3B	−2,2	ACTA2	−1,52	MRPL13	−1,59	PRED.: LOC100859143	−1,77
ALDH1A3	−2,1	LOC100858370	−1,46	CACNB4	−1,58	PTPRZ1	−1,75
STXBP5L	−2,1	MIR1648	−1,43	ABI3BP	−1,56	COCH	−1,70
IFIT5	−2,0	ACTG2	−1,41	VH57–1	−1,51	Mt_tRNA	−1,69
OASL	−1,9	SLC8A3	−1,41	LOC107050168	−1,51	PRED.: TMEM98	−1,67
MDK	−1,8	LOC776492	−1,40	LACC1	−1,50	LECT1	−1,65
MI0005509	−1,8	OLFML3	−1,39	LOC107055505	−1,45	PRED.: OR14A16L45	−1,64
SNORD18	−1,7	TMC6	−1,37	KCNK12	−1,45	SLC38A3	−1,63