Table 2.
Baseline predisposition characteristics of overall cohort and five major site subgroups. BMI body mass index, ESRD end-stage renal disease
| Overall, n = 316 | Abdominal, n = 140 (44%) | Pulmonary, n = 59 (19%) | S/ST, n = 56 (18%) | GU, n = 40 (12%) | Vascular, n = 21 (7%) | p value | |
|---|---|---|---|---|---|---|---|
| Male, n (%) | 173 (55) | 68 (49) | 42 (71) | 28 (50) | 20 (50) | 15 (71) | 0.02 |
| Age in years, median (25th, 75th) | 62 (50,70) | 63 (50,71) | 62 (54,68) | 56 (44,64) | 61 (51,73) | 69 (58,73) | 0.03 |
| Age ≥ 65 years, n (%) | 125 (40) | 60 (43) | 22 (37) | 12 (21) | 18 (45) | 13 (62) | < 0.01 |
| Race, n (%) | 0.39 | ||||||
| Caucasian (White) | 283 (90) | 127 (91) | 56 (95) | 47 (84) | 34 (85) | 19 (90) | |
| African American | 28 (9) | 10 (7) | 3 (5) | 8 (14) | 6 (15) | 1 (5) | |
| Other | 5 (1) | 3 (2) | 0 (0) | 1 (2) | 0 (0) | 1 (5) | |
| Hispanic ethnicity | 8 (3) | 3 (2) | 1 (2) | 2 (4) | 1 (3) | 1 (4) | |
| BMI, median (25th, 75th) | 29 (25,37) | 28 (24,34) | 29 (24,33) | 35 (28,43) | 34 (26,39) | 28 (25,33) | < 0.01 |
| Number of comorbidities | |||||||
| 1 | 65 (21) | 28 (20) | 14 (24) | 14 (25) | 7 (18) | 2 (10) | 0.61 |
| 2 | 65 (21) | 34 (24) | 12 (20) | 9 (16) | 7 (18) | 3 (14) | 0.69 |
| ≥ 3 | 134 (42) | 57 (41) | 23 (39) | 23 (41) | 17 (43) | 14 (67) | 0.25 |
| Charlson comorbidity index, median (25th, 75th) | 3 (1,5) | 3 (1,5) | 3 (1,4) | 2 (1,4) | 3 (1,5) | 4 (3,7) | 0.07 |
| Type of comorbidities | |||||||
| Hypertension | 195 (62) | 86 (61) | 41 (70) | 28 (50) | 24 (60) | 16 (77) | 0.16 |
| Diabetes | 109 (34) | 44 (31) | 14 (24) | 30 (54) | 14 (35) | 7 (33) | 0.02 |
| Coronary artery disease | 80 (25) | 32 (23) | 16 (27) | 11 (20) | 10 (25) | 11 (52) | 0.07 |
| Chronic lung disease | 62 (20) | 32 (23) | 17 (29) | 6 (11) | 1 (2) | 6 (29) | < 0.01 |
| Morbid obesity | 56 (18) | 22 (16) | 7 (12) | 17 (30) | 8 (20) | 2 (10) | 0.08 |
| Chronic renal disease | 44 (14) | 17 (12) | 7 (12) | 9 (16) | 6 (15) | 5 (24) | 0.60 |
| ESRD | 8 (3) | 3 (2) | 2 (3) | 1 (2) | 0 (0) | 2 (10) | 0.25 |
| Atrial fibrillation | 38 (12) | 17 (12) | 4 (7) | 8 (14) | 5 (12) | 4 (19) | 0.54 |
| Peripheral artery disease | 38 (12) | 12 (9) | 6 (10) | 5 (9) | 4 (10) | 11 (53) | < 0.01 |
| Heart failure | 37 (12) | 13 (9) | 8 (14) | 8 (14) | 3 (8) | 5 (24) | 0.28 |
| Prior Stroke | 24 (8) | 15 (11) | 5 (8) | 2 (4) | 2 (5) | 0 (0) | 0.33 |
| Substance abuse | 21 (7) | 11 (8) | 5 (8) | 3 (5) | 0 (0) | 2 (10) | 0.32 |
| Dementia | 7 (2) | 3 (2) | 2 (3) | 0 (0) | 1 (2) | 1 (5) | 0.49 |
| Liver cirrhosis | 6 (2) | 2 (1) | 2 (3) | 1 (2) | 1 (2) | 0 (0) | 0.85 |
| History of cancer, n (%) | 82 (26) | 46 (33) | 14 (24) | 9 (16) | 10 (25) | 3 (14) | 0.10 |
| Active cancer, n (%) | 47 (15) | 30 (21) | 9 (15) | 3 (5) | 5 (12) | 0 (0) | < 0.01 |
| Reason for hospital admission, n (%) | |||||||
| Active infection | 188 (60) | 93 (66) | 4 (7) | 51 (91) | 23 (58) | 17 (81) | < 0.01 |
| Elective surgery | 64 (20) | 29 (21) | 18 (31) | 3 (5) | 12 (30) | 2 (9) | < 0.01 |
| Trauma | 33 (10) | 5 (4) | 25 (42) | 1 (2) | 1 (2) | 1 (5) | < 0.01 |
| Chronic health condition | 31 (10) | 13 (9) | 12 (20) | 1 (2) | 4 (10) | 1 (5) | 0.02 |
| Inter-facility hospital transfer, n (%) | 129 (40.8) | 64 (45.7) | 19 (32.2) | 21 (37.5) | 6 (15) | 19 (90.5) | < 0.01 |