Table 2.

Characteristics at baseline, clinical cognitive profile and MRI findings at 1 year in stroke survivors by PET or no PET at 7 years

	PET	NO PET	P value
N	26	85
Male (%)	18 (69)	43 (51)	0.227
Mean age, years (SD)	72.9 (7.0)	75.9 (11.8)	0.239
Less than 9 years of education (%)	4 (15)	18 (21)	0.776
Living alone (%)	4 (15)	24 (28)	0.288
Stroke subtype (%)			0.926
Cerebral infarction	20 (77)	66 (78)
TIA	4 (15)	11 (13)
Cerebral hemorrhage	2 (8)	8 (9)
TOAST classification (%)			0.724
Large-vessel disease	2 (8)	12 (14)
Cardio-embolic disease	8 (31)	19 (22)
Small-vessel disease	9 (35)	29 (34)
Stroke of undetermined etiology	7 (27)	25 (30)
Assessments. Mean (SD) (n)
NIHSS	1.12 (2.1) (26)	1.99 (3.6) (85)	0.247
mRS	1.0 (1.2) (26)	1.26 (1.2) (85)	0.266
IQCODE	3.0 (0.1) (26)	3.1 (0.2) (85)	0.641
MMSE	27.8 (2.1) (26)	26.5 (4.0) (82)	0.113
Clinical profile 12 months
Dementia	1 (26)	13 (84)	0.223
MCI	6 (26)	31 (84)	0.286
Normal cognition	19 (26)	40 (84)	0.040
MRI 12 months. Mean (SD) (n)
MTLA grade	0.79 (0.8) (24)	1.18 (1.2) (77)	0.135
Fazekas score	1.52 (0.8) (25)	1.86 (0.9) (76)	0.095
Global Cortical Atrophy	1.28 (0.7) (25)	1.48 (0.6) (75)	0.177
CSF (Aβ)-42 (ng/L) 12 months (n)	840 (250) (13)	861 (302) (41)	0.824
CSF total tau (ng/L) 12 months (n)	270 (101) (13)	387 (192) (41)	0.040

TIA = Transient Ischemic Attack; TOAST = the trial of org 10,172 in acute stroke treatment classification; NIHSS=National Institute of Health Stroke Scale; BI=Barthel Activities of Daily Living Index; mRS = modified Rankin scale; IQCODE = the informant questionnaire on cognitive decline in the elderly; MMSE = Mini Mental State Examination; SD = standard deviation;MCI = mild cognitive impairment; MTLA = medial temporal lobe atrophy. CSF (Aβ)-42 = cerebrospinal fluid amyloid-β peptide