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. 2020 May 8;20:402. doi: 10.1186/s12885-020-06906-1

Table 5.

Multivariable analysis: competing risk regression for LC, Cox regression for lung PFS and OS (distant PFS . Hazard ratio and p-value are reported only for the variables included in the multivariable analysis

Endpoint Local control Lung PFS Overall survival
Variables Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value
Primary histology (adeno vs other) 0.75 (0.28–2.02) 0.57 0.54 (0.28–1.07) 0.078 0.57 (0.22–1.50) 0.25
Primary tumor site (reference: Lung)
GI vs Lung 0.55 (0.14–2.09) 0.38 0.90 (0.43–1.88) 0.77 0.29 (0.08–1.02) 0.05
Other vs Lung 1.00 (0.39–2.53) 0.99 0.61 (0.27–1.38) 0.24 0.37 (0.11–1.31) 0.12
Prior chemotherapy (yes vs no) 3.01 (0.76–11.92) 0.12 / / / /
Age > 65 (yes vs no) 0.64 (0.24–1.67) 0.36 / / / /
Performance status(1+ vs 0) 4.00 (0.86–18.64) 0.077 / / 2.46 (0.56–10.74) 0.23
Gender (male vs female) 2.17 (0.86–5.44) 0.10 / / / /
GTV volume (> 10 cc vs < 10 cc) 1.92 (0.78–4.75) 0.16 / / / /
BED prescription (> 120 Gy vs < 120 Gy) 0.35 (0.14–0.87) 0.025 / / / /