Table 4.

K-ras mutations in aberrant crypt foci and normal colon mucosa of AOM-treated and phytate-fed rats

Group (n)	Mutation type at Codon 12 (number of ACF/normal mucosa samples analyzed)	Mutation type at Codon 13 (number of ACF/normal mucosa samples analyzed)
Control (8)	GGT-GAT 0% (0/24), GGT-GTT 0% (0/24)	GGC-CGC 0% (0/24)
AOM (20)	GGT-GAT 60% (24/40), GGT-GTT 40% (16/40)	GGC-CGC 18% (7/40)
AOM+1% phytate (20)	GGT-GAT 30% (12/40), GGT-GTT 10% (4/40)	GGC-CGC 0% (0/24)
AOM+2% phytate (20)	GGT-GAT 10% (4/40), GGT-GTT 5% (2/40)	GGC-CGC 0% (0/24)

AOM: Azoxymethane, ACF: Aberrant crypt foci