Table 1.

Minimum inhibitory concentration (MIC)of antibiotics against Streptococcus pyogenes

Antibiotic Group	Antibiotics	MIC Range (µg/ml)	MIC50 (µg/ml)	MIC90 (µg/ml)	Breakpoint (Sensitive/ Resistance)	Level of resistance (No. of times)
MIC break points are according to CLSI, 2015 and NCCLS
Lincosamide	Clindamycin	4- >1024	64	>1024	<0.25/>1	1024
Macrolides	Azithromycin	4 - >1024	32	512	<0.5/>2	512
	Clarithromycin	1 - 128	2	32	<0.25/>1	128
Quinolone	Ciprofloxacin	4- 32	8	32	<1/>4	8