Table 3.
Means and standard deviations of biochemical parameters (baseline, after treatment, and percentage of change by treatment) for the genotype of rs2241766.
| Parameter | Genotypes | P value | |
|---|---|---|---|
| TT, mean (SD) | TG/GG, mean (SD) | ||
| HDL (mmol/L) | |||
| Baseline | 1.44 (0.377) | 1.42 (0.315) | 0.930 |
| After treatment | 1.304 (0.310) | 1.34 (0.327) | 0.553 |
| % change by treatment | −7.4% (14.86) | −4.2% (19.41) | 0.129 |
|
| |||
| LDL (mmol/L) | |||
| Baseline | 2.35 (0.70) | 2.32 (0.67) | 0.275 |
| After treatment | 2.85 (0.75) | 2.74 (0.83) | 0.570 |
| % change by treatment | 2.5% (25.7) | 1.9% (20.9) | 0.699 |
|
| |||
| TChol (mmol/L) | |||
| Baseline | 4.22 (0.85) | 4.03 (1.08) | 0.636 |
| After treatment | 4.71 (0.91) | 4.57 (1.10) | 0.339 |
| % change by treatment | 12.8% (14.4) | 1.6% (20.4) | 0.074 |
|
| |||
| TG (mmol/L) | |||
| Baseline | 0.99 (0.57) | 1.00 (0.66) | 0.642 |
| After treatment | 1.31 (0.71) | 1.27 (0.71) | 0.872 |
| % change by treatment | 43.3% (58.76) | 42.3% (78.0) | 0.219 |
|
| |||
| AST (U/I) | |||
| Baseline | 19.5 (6.60) | 17.59 (4.00) | 0.118 |
| After treatment | 21.84 (7.64) | 20.39 (7.77) | 0.337 |
| % change by treatment | 15.3% (35.0) | 16.5% (30.7) | 0.664 |
|
| |||
| ALT (U/I) | |||
| Baseline | 16.25 (8.34) | 14.97 (7.63) | 0.338 |
| After treatment | 17.17 (8.26) | 18.20 (14.73) | 0.142 |
| % change by treatment | 13.2% (46.04) | 21.5% (51.88) | 0.396 |
Student's t-test was used. P value is significant at less than 0.05. HDL: high-density lipoprotein. LDL: low-density lipoprotein. TChol: total cholesterol. AST: aspartate aminotransferase. ALT: alanine aminotransferase.