Table 4.
Means and standard deviations of biochemical parameters (baseline, after treatment, and percentage of change by treatment) for the genotype of rs1501299.
| Parameter | Genotypes | P value | |
|---|---|---|---|
| GG, mean (SD) | GT, mean (SD) | ||
| HDL (mmol/L) | |||
| Baseline | 1.42 (0.366) | 1.453 (0.358) | 0.690 |
| After treatment | 1.29 (0.305) | 1.35 (0.322) | 0.574 |
| % change by treatment | −8.2% (13.5) | −5.6% (18.6) | 0.0076 |
|
| |||
| LDL (mmol/L) | |||
| Baseline | 2.33 (0.598) | 2.36 (0.779) | 0.082 |
| After treatment | 2.80 (0.684) | 2.85 (0.826) | 0.217 |
| % change by treatment | 22.3% (23.5) | 24.2% (25.8) | 0.709 |
|
| |||
| TChol (mmol/L) | |||
| Baseline | 4.11 (0.868) | 4.24 (0.959) | 0.333 |
| After treatment | 4.60 (0.874) | 4.75 (1.045) | 0.216 |
| % change by treatment | 13.8% (17.1) | 13.3% (15.2) | 0.869 |
|
| |||
| TG (mmol/L) | |||
| Baseline | 0.99 (0.56) | 0.99 (0.63) | 0.395 |
| After treatment | 1.25 (0.68) | 1.36 (0.74) | 0.572 |
| % change by treatment | 36.7% (64.7) | 49.7% (62.9) | 0.767 |
|
| |||
| AST (U/I) | |||
| Baseline | 19.15 (5.26) | 18.85 (6.88) | 0.456 |
| After treatment | 21.54 (6.99) | 21.39 (8.39) | 0.618 |
| % change by treatment | 15.3% (36.2) | 15.9% (31.4) | 0.808 |
|
| |||
| ALT (U/I) | |||
| Baseline | 15.56 (6.20) | 16.30 (9.85) | 0.093 |
| After treatment | 16.73 (7.69) | 18.17 (12.45) | 0.268 |
| % change by treatment | 12.8% (47.6) | 18.0% (47.6) | 0.819 |
∗Student's t-test was used. P value is significant at less than 0.05. HDL: high-density lipoprotein. LDL: low-density lipoprotein. TChol: total cholesterol. AST: aspartate aminotransferase. ALT: alanine aminotransferase.