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Physical and biochemical analysis of rats. The diabetic model was established by increased blood glucose (a) and reduced body weight (b). Renal function of rats was assessed by 24-hour urinary total protein (c), serum creatinine (d), blood urea nitrogen (e), and urinary protein/creatinine ratio (f) (n = 4~5, ∗p < 0.05 versus control group, ∗∗p < 0.01 versus control group, and #p < 0.05 versus DN group).
