Ablation of Ctnnb1 completely suppresses c-Met/sgAxin1-driven mouse hepatocarcinogenesis. (A) Study design. (B) Survival analysis of Ctnnb1+/+ mice (n = 10) and Ctnnb1f/f mice (n = 10) using the Kaplan-Meier survival method. (C) Liver body weight ratio between two groups. Data are presented as mean ± SD. ***, P < 0.001. (D) Gross images of livers, H&E staining, and Ki-67 staining in Ctnnb1+/+ and Ctnnb1f/f mice livers. Magnifications: ×100, scale bar: 200 μm; ×200, scale bar: 100 μm. Abbreviation: H&E, hematoxylin and eosin.