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. 2020 Mar 26;8(1):e000548. doi: 10.1136/jitc-2020-000548

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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[⁸⁹Zr]Zr-N-suc-Df-ERY974 distribution in time. (A) Maximal intensity projection images of [⁸⁹Zr]Zr-N-suc-Df-ERY974 in HepG2 tumor (white dotted circle) bearing NOG mice at 24 hours, 72 hours, 120 hours and 168 hours post 10 µg [⁸⁹Zr]Zr-N-suc-Df-ERY974 injection. (B) Quantification of tumor and blood pool (n=6). data shown as median SUV_mean and IQR. (C) Tumor-to-blood ratio based on SUV_mean. Data shown as median tumor-to-blood ratio and IQR. Cr, cranial; Ca, caudal; H, heart; L, liver; SUV_mean, standardised uptake value; T, tumor.