Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 30;26:e920668-1–e920668-14. doi: 10.12659/MSM.920668

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Med Sci Monit, 2020

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

PMC Copyright notice

The effect of carbon monoxide (CO) on the survival rate in the rat model of sepsis induced by cecal ligation and puncture (CLP). Rats from each study group (n=10) were assessed to determine the 7-day survival rate. The Kaplan-Meier survival curves are shown. Male Sprague-Dawley rats (n=120) were divided into six study groups: the sham group; the CLP group; the hemin group (treated with ferric chloride and heme); the zinc protoporphyrin IX (ZnPPIX) group; the CO-releasing molecule 2 (CORM-2) group; and the inactive CORM-2 (iCORM-2) group. FD-4 – fluorescein isothiocyanate-labeled dextran 3000~4000 KDa; CLP – cecal ligation and puncture; CORM-2 – CO-releasing molecule 2; Hemin – ferric chloride heme; ZnPPIX – zinc protoporphyrin IX; iCORM-2 – inactive CORM-2.