| 1.1 Primary outcome: adherence, grouped by types of interventions (dichotomous) |
18 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.1.1 Educational interventions |
2 |
182 |
Risk Ratio (M‐H, Random, 95% CI) |
1.66 [1.33, 2.06] |
| 1.1.2 Behavioural interventions |
4 |
528 |
Risk Ratio (M‐H, Random, 95% CI) |
1.22 [1.07, 1.38] |
| 1.1.3 Mixed educational and behavioural interventions |
12 |
3147 |
Risk Ratio (M‐H, Random, 95% CI) |
1.22 [1.08, 1.37] |
| 1.2 Primary outcome: adherence, grouped by types of interventions (continuous) |
12 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.2.1 Educational interventions |
5 |
1165 |
Std. Mean Difference (IV, Random, 95% CI) |
0.16 [‐0.12, 0.43] |
| 1.2.3 Mixed educational and behavioural interventions |
7 |
1825 |
Std. Mean Difference (IV, Random, 95% CI) |
0.47 [‐0.08, 1.02] |
| 1.3 Primary outcome: adherence, mixed interventions, grouped by intervention duration (dichotomous) |
11 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.3.1 Short duration (≤ 3 months) |
6 |
486 |
Risk Ratio (M‐H, Random, 95% CI) |
1.40 [1.13, 1.74] |
| 1.3.2 Long duration (> 3 months) |
5 |
2505 |
Risk Ratio (M‐H, Random, 95% CI) |
1.11 [0.97, 1.27] |
| 1.4 Primary outcome: adherence, mixed interventions, grouped by intervention duration (continuous) |
7 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.4.1 Short duration (≤ 3 months) |
3 |
398 |
Std. Mean Difference (IV, Random, 95% CI) |
0.18 [‐0.52, 0.88] |
| 1.4.2 Long duration (> 3 months) |
4 |
1427 |
Std. Mean Difference (IV, Random, 95% CI) |
0.70 [‐0.25, 1.65] |
| 1.5 Primary outcome: adherence, mixed interventions, grouped by subjective or objective outcome measures (dichotomous) |
12 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.5.1 Objective outcome measure |
5 |
762 |
Risk Ratio (M‐H, Random, 95% CI) |
1.13 [0.93, 1.38] |
| 1.5.2 Subjective outcome measure |
7 |
2385 |
Risk Ratio (M‐H, Random, 95% CI) |
1.26 [1.09, 1.46] |
| 1.6 Primary outcome: adherence, mixed interventions, grouped by subjective or objective outcome measure (continuous) |
7 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.6.1 Objective outcome measure |
3 |
360 |
Std. Mean Difference (IV, Random, 95% CI) |
0.82 [‐0.49, 2.13] |
| 1.6.2 Subjective outcome measure |
4 |
1465 |
Std. Mean Difference (IV, Random, 95% CI) |
0.21 [‐0.23, 0.66] |
| 1.7 Primary outcome: adherence, mixed interventions, grouped by provider (dichotomous) |
12 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.7.1 Provider: pharmacist |
8 |
2672 |
Risk Ratio (M‐H, Random, 95% CI) |
1.21 [1.04, 1.41] |
| 1.7.2 Provider: nurse |
2 |
297 |
Risk Ratio (M‐H, Random, 95% CI) |
1.19 [1.02, 1.38] |
| 1.7.3 Provider: 2 or more health professionals |
2 |
178 |
Risk Ratio (M‐H, Random, 95% CI) |
1.38 [0.88, 2.16] |
| 1.8 Primary outcome: adherence, mixed interventions, grouped by provider (continuous) |
6 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.8.1 Provider: pharmacist |
2 |
286 |
Std. Mean Difference (IV, Random, 95% CI) |
1.38 [0.01, 2.75] |
| 1.8.2 Provider: nurse |
2 |
140 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.13 [‐0.53, 0.27] |
| 1.8.3 Provider: 2 or more health professionals |
2 |
324 |
Std. Mean Difference (IV, Random, 95% CI) |
0.42 [‐0.38, 1.21] |
| 1.9 Secondary outcome: ED/Hospital admissions, grouped by type of intervention (dichotomous) |
16 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.9.1 Educational interventions |
3 |
554 |
Risk Ratio (M‐H, Random, 95% CI) |
1.02 [0.71, 1.48] |
| 1.9.2 Behavioural interventions |
2 |
70 |
Risk Ratio (M‐H, Random, 95% CI) |
0.21 [0.08, 0.55] |
| 1.9.3 Mixed educational and behavioural interventions |
11 |
1827 |
Risk Ratio (M‐H, Random, 95% CI) |
0.67 [0.50, 0.90] |
| 1.10 Secondary outcome: mortality, mixed interventions |
7 |
1776 |
Risk Ratio (M‐H, Random, 95% CI) |
0.93 [0.67, 1.30] |
