1. aged.id.

2. ((old or older or aged or senior) adj2 (person? or people or adult? or men or women or patient* or consumer* or carer* or caregiver* or care giver*)).ti,ab,id.

3. (late life or ag?ing or old age or seniors).ti,ab,hw,id.

4. (elder* or geriatric* or gerontolog* or geropsych* or veteran*).mp.

5. ("380" or "390").ag.

6. or/1‐5

7. exp drugs/

8. exp pharmacology/

9. (medication* or medicine? or medicament* or pharmac* or drug? or polypharmac*).ti,ab,hw,id.

10. exp drug therapy/

11. or/7‐10

12. 6 and 11

13. primary health care/

14. (primary adj2 (care or healthcare)).ti,ab,id.

15. exp outpatient treatment/

16. ambulatory.ti,ab,id.

17. family medicine/

18. general practitioners/

19. gp?.ti,ab,id.

20. family physicians/

21. ((general or family) adj practi*).ti,ab,id.

22. home care/

23. exp community services/

24. long term care/

25. aftercare/

26. exp facility discharge/

27. ((patient or hospital) adj3 discharge).ti,ab,hw,id.

28. "continuum of care"/

29. (community or home* or domicil* or outreach or out‐reach or postdischarge or post‐discharge or postacute or post‐acute or discharge plan* or aftercare or after care).ti,ab,hw,id.

30. or/13‐29

31. 12 and 30

32. client education/

33. ((educat* or instruct* or advis* or advice* or counsel* or teach* or train* or coach* or learn*) and (patient* or client* or consumer* or user* or carer* or caregiver* or care giver*)).mp.

34. exp counseling/

35. information services/

36. information/

37. (inform* adj5 (patient* or client* or consumer* or user* or carer* or caregiver* or care giver*)).ti,ab,id.

38. (reminder? or reminder system*).ti,ab,id.

39. warning labels/

40. "prescribing (drugs)"/

41. ((patient* or client* or consumer* or user* or subject? or carer* or caregiver* or care giver*) and (manag* adj5 (medication* or medicines))).ti,ab,hw,id.

42. pharmac* care.ti,ab,id.

43. or/32‐42

44. treatment compliance/

45. ((medication or treatment) adj (complian* or adheren* or noncomplian* or nonadheren*)).ti,ab,id.

46. self efficacy/

47. ((patient* or client* or consumer* or user* or subject? or carer* or caregiver* or care giver*) and (competen* or confident or confidence or abilit* or capacit* or skill* or self‐efficacy or cope? or coping or complian* or noncomplian* or adher* or nonadher* or underadheren* or concordan* or nonconcordan* or persisten* or nonpersist*)).ti,ab,hw,id.

48. ((patient* or client* or consumer* or user* or subject? or carer* or caregiver* or care giver*) and (error* or mistak* or misus* or mismanag*)).ti,ab,hw,id.

49. drug self‐administration/

50. or/44‐49

51. 31 and (43 or 50)

52. random*.ti,ab,hw,id.

53. trial*.ti,ab,hw,id.

54. controlled stud*.ti,ab,hw,id.

55. placebo*.ti,ab,hw,id.

56. ((singl* or doubl* or trebl* or tripl*) and (blind* or mask*)).ti,ab,hw,id.

57. (cross over or crossover or factorial* or latin square).ti,ab,hw,id.

58. (assign* or allocat* or volunteer*).ti,ab,hw,id.

59. treatment effectiveness evaluation/

60. mental health program evaluation/

61. exp experimental design/

62. "2100".md.

63. or/52‐62

64. 51 and 63