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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Acta Biomater. 2020 Apr 5;108:153–167. doi: 10.1016/j.actbio.2020.03.035

Fig. 3.

Fig. 3.

Mouse BMSCs proliferated on 3D RAS and VAS. (A) The distribution of mouse BMSCs in the center and the edge of 1-mm thick, RAS or VAS after culturing for 9 days. (B) The rapid proliferation of mouse BMSCs on 1-mm thick, RAS and VAS after culturing for 1, 5, 9 and 14 days, respectively (n=6). (C) The increased expression of growth factors (VEGF, PDGF-BB, bFGF), migration related genes (TGF-β1, CXCR4), and decreased expression of type 1 collagen of BMSCs cultured on 1-mm thick, RAS or VAS for 5 and 9 days (n=9). RAS: Radially aligned scaffolds, VAS: Vertically aligned scaffolds. The data are presented as the mean ± S.D. *p<0.05, **p<0.01.