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. 2019 Jun 3;29(5):324–339. doi: 10.1089/cap.2019.0043

Table 1.

Immediate-Release Formulations: Methylphenidate

Drug Formulation(s) Dose range Comments
MPH oral solution 5 mg/5 mL and 10 mg/5 mL solutions • Starting dose:
4–5-year old: 2.5–5 mg
6 years and older: 5–10 mg
• Dosage range:
4–5-year old: 2.5–30 mg/day
6 years and older: 5–60 mg/day. Given in divided dose qd-tid
• Dose can be increased by 5–10 mg/day weekly
• Max dose 60 mg/day
• Dose the same as other dl-MPH formulations
• Onset of response 30–45 minutes
• Duration of response 3–4 hours postdose
• Multiple manufacturers
MPH chewable tablet 2.5, 5, and 10 mg tablets • Starting dose:
4–5-year old: 2.5–5 mg
6 years and older: 5–10 mg
• Dosage range:
4–5-year old: 2.5–30 mg/day
6 years and older: 5–60 mg/day. Given in divided dose qd-tid
• Dose can be increased by 5–10 mg/day weekly
• Max dose 60 mg/day
• Dose the same as other dl-MPH formulations
• Onset of response 30–45 minutes
• Duration of response 3–4 hours postdose
• Multiple manufacturers
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