29. Survival at predefined time points for all cancer patients, long term follow up studies only*.
On study mortality data set | Overall survival data set | |||||
Time after date of randomization | Deaths | ESA versus control HR (95% CI)** | P value | Deaths | ESA versus control HR (95% CI)* | P value |
At 4 months | 790 | 1.22 (95% CI 1.06‐1.41) | 0.005 | 965 | 1.17 (95% CI 1.03‐1.33) | 0.015 |
At 8 months | 970 | 1.25 (95% CI 1.10‐1.42) | 0.001 | 2023 | 1.08 (95% CI 0.99‐1.18) | 0.097 |
At 12 months | 1050 | 1.26 (95% CI 1.11‐1.42) | <0.001 | 2823 | 1.08 (95% CI 1.00‐1.16) | 0.046 |
At 24 months | ‐ | ‐ | ‐ | 3743 | 1.07 (95% CI 1.01‐1.15) | 0.032 |
At 36 months | ‐ | ‐ | ‐ | 4028 | 1.06 (95% CI 0.99‐1.13) | 0.077 |
At 60 months | ‐ | ‐ | ‐ | 4169 | 1.07 (95% CI 1.00‐1.13) | 0.041 |
*8974 patients from all treatment populations stemming from trials designed for long term follow up were under observation. **based on Cox fixed‐effects model stratified by study