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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Osterborg 1996.

Methods randomized controlled trial, not placebo‐controlled
Participants n = 148, multiple myeloma, Non‐Hodgkin lymphoma, chronic lymphocytic lymphoma; concomitant treatment: chemotherapy
Interventions drug = Epoetin beta
dose = a: 10000 IU sc 7x/week, b: titration
hb‐target = 10‐14 g/dL (women), 10‐13 g/dL (men)
planned ESA duration = 24 weeks
Outcomes Primary: transfusion; secondary: safety, Hb
Notes study number = 43680
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk no description
Allocation concealment? Low risk central randomization