Razzouk 2006.
Methods | randomized controlled trial, placebo‐controlled | |
Participants | n = 126, solid tumors, Hodgkin disease, Non‐Hodgkin lymphoma (patients excluded from the present meta‐analysis), acute lymphocytic leukemia (patients excluded from the present meta‐analysis); concomitant treatment: chemotherapy | |
Interventions | drug = Epoetin alpha dose = 600 IU/kg iv weekly hb‐target = 13‐15 g/dL (age > 12 years), 13‐14 g/dL (age <12 years) planned ESA duration = 16 weeks |
|
Outcomes | Primary: QoL; secondary: Hb, transfusion | |
Notes | study number = 80515 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | computer generated |
Allocation concealment? | Low risk | central randomization and coded drug packs of identical appearance |