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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Razzouk 2006.

Methods randomized controlled trial, placebo‐controlled
Participants n = 126, solid tumors, Hodgkin disease, Non‐Hodgkin lymphoma (patients excluded from the present meta‐analysis), acute lymphocytic leukemia (patients excluded from the present meta‐analysis); concomitant treatment: chemotherapy
Interventions drug = Epoetin alpha
dose = 600 IU/kg iv weekly
hb‐target = 13‐15 g/dL (age > 12 years), 13‐14 g/dL (age <12 years)
planned ESA duration = 16 weeks
Outcomes Primary: QoL; secondary: Hb, transfusion
Notes study number = 80515
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk computer generated
Allocation concealment? Low risk central randomization and coded drug packs of identical appearance