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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Rose 1994.

Methods randomized controlled trial, placebo‐controlled
Participants n = 221, chronic lymphocytic leukemia (stage III, IV); concomitant therapy: other
Interventions drug = Epoetin alpha
dose = 150 IU/kg sc TIW
hb‐target = Hct 38%‐40%
planned ESA duration = 12 weeks
Outcomes Primary: Hct; secondary: transfusion, QoL, safety
Notes study number = 98358
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk computer‐generated
Allocation concealment? Unclear risk no description