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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Ten Bokkel Huinink 1998.

Methods randomized controlled trial, not placebo‐controlled
Participants n = 120, ovarian cancer (stage II‐IV); concomitant treatment: chemotherapy
Interventions drug = Epoetin beta
dose = a: 150 IU/kg sc TIW, b: 300 IU/kg sc TIW
hb‐target = 14‐15 g/dL
planned ESA duration = during chemotherapy
Outcomes Primary: transfusion; secondary: Hb, reticulocytes, Hct, safety
Notes study number = 47852
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk no description
Allocation concealment? Low risk central randomization