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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Thomas 2002.

Methods randomized controlled trial, not placebo‐controlled
Participants n = 130, breast, gastrointestinal, gynecological, other cancer; concomitant treatment: chemotherapy
Interventions drug = Epoetin alpha
dose = if body weight > 45 kg 10000 IU sc TIW, if body weight < 45 kg 5000 IU sc TIW
hb‐target = 12‐14 g/dL
planned ESA duration = 12 weeks
Outcomes Primary: Hb response; secondary: QoL, tumor response, survival, safety
Notes study number = 84090
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk no description
Allocation concealment? Low risk central randomization