| Two‐stage meta‐analysis based on random‐ effects Cox model | Study 83322 in radiochemotherapy treatment group | Study 83322 in mixed treatment group | Study 83322 in chemotherapy treatment group |
| ESA versus control | HR (95% CI) | HR (95% CI) | HR (95% CI) |
| Chemotherapy | 1.09 (0.97‐1.23) | 1.09 ( 0.97‐1.23) | 1.10 (0.98‐1.24) |
| Radiochemotherapy | 1.47 (0.83‐2.59) | 2.34 (0.42‐13.03) | 2.34 (0.42‐13.03) |
| Radiotherapy | 1.51 (0.73‐3.12) | 1.51 (0.73‐3.12) | 1.51 (0.73‐3.12) |
| Mixed | 1.50 (0.62‐3.66) | 1.42 (0.86‐2.34) | 1.50 (0.62‐3.66) |
| None | 1.32 (1.06‐1.65) | 1.32 (1.06‐1.65) | 1.32 (1.06‐1.65) |
| Overall | 1.16 (1.05‐1.29) | 1.16 (1.05‐1.29) | 1.16 (1.05‐1.29) |
| LR test | 0.4234 | 0.3607 | 0.4290 |
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