| Two‐stage meta‐analysis based on random‐effects Cox model | ESA versus control HR (95% CI) |
| Baseline Hb < 10 g/dL & Hb no change | 1.08 (95% CI 0.90‐1.30) |
| Baseline Hb < 10 g/dL & Hb increase | 1.18 (95% CI 0.70‐1.98) |
| Baseline Hb 10‐12 g/dL & Hb decrease | 1.02 (95% CI 0.70‐1.50) |
| Baseline Hb 10‐12 g/dL & Hb no change | 1.13 (95% CI 0.91‐1.40) |
| Baseline Hb > 12 g/dL & Hb decrease | 1.21 (95% CI 0.91‐1.61) |
| Baseline Hb > 12 g/dL & Hb no change | 1.44 (95% CI 1.11‐1.88) |
| Unclear/not reported | 0.62 (95% CI 0.16‐2.43) |
| Overall | 1.16 (95% CI 1.05‐1.29) |
| LR test | 0.6180 |
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