Two‐stage meta‐analysis based on random‐effects Cox model	ESA versus control HR (95% CI)
Baseline Hb < 10 g/dL & Hb no change	1.00 (95% CI 0.50‐2.00)
Baseline Hb < 10 g/dL & Hb increase	1.07 (95% CI 0.88‐1.30)
Baseline Hb 10‐12 g/dL & Hb no change	1.17 (95% CI 0.83‐1.64)
Baseline Hb 10‐12 g/dL & Hb increase	1.10 (95% CI 0.84‐1.46)
Baseline Hb > 12 g/dL & Hb decrease	1.04 (95% CI 0.48‐2.24)
Baseline Hb > 12 g/dL & Hb no change	1.25 (95% CI 1.02‐1.53)
Baseline Hb > 12 g/dL & Hb increase	1.93 (95% CI 0.66‐5.67)
Unclear/not reported	0.62 (95% CI 0.16‐2.43)
Overall	1.16 (95% CI 1.05‐1.29)
LR test	0.8420