Cazzola 1995.
Methods | randomized controlled trial, not placebo‐controlled | |
Participants | n = 143, multiple myeloma, Non‐Hodgkin lymphoma; concomitant treatment: chemotherapy | |
Interventions | drug = Epoetin beta dose = a: 1000 IU sc 7x/week, b: 2000 IU sc 7x/week; c: 5000 IU sc 7x/ week; d: 10000 IU sc 7x/week hb‐target = 11‐13 g/dL (MM), 11‐15 g/dL (NHL) planned ESA duration = 8 weeks |
|
Outcomes | Primary: Hb response; secondary: Hb, Hct, reticulocytes, iron, ferritin, safety | |
Notes | study number = 37653 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | randomization list |
Allocation concealment? | Low risk | central randomization |