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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

Charu 2007.

Methods randomized controlled trial, not placebo‐controlled
Participants n = 287, lymphoma, breast, lung, gastrointestinal, genitourinary, gynecologic, other cancer; no anticancer therapy
Interventions drug = Darbepoetin alpha
dose = 3.0 µg/kg sc Q2W
hb‐target = 13‐14 g/dL (women), 13‐15 g/dL (men)
planned ESA duration = 12 weeks
Outcomes Primary: hospitalization days; secondary: costs, QoL, transfusion, Hb, safety
Notes study number = 53081
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk no description
Allocation concealment? Low risk central randomization