Dammacco 2001.
Methods | randomized controlled trial, placebo‐controlled | |
Participants | n = 145, multiple myeloma; concomitant treatment: chemotherapy | |
Interventions | drug = Epoetin alpha dose = 150 IU/kg sc TIW hb‐target = 12‐14 g/dL planned ESA duration = 12 weeks |
|
Outcomes | Primary: transfusion; secondary: Hb, Hct, reticulocytes, serum erythropoietin levels, QoL | |
Notes | study number = 11220 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | randomization schedule prepared by RWJPRI |
Allocation concealment? | Unclear risk | two randomization lists (patients previously transfused or not), when patient enters the study the next number was to be assigned |