Grote 2005.

Methods	randomized controlled trial, placebo‐controlled
Participants	n = 224, small cell lung cancer (limited and extensive disease); concomitant treatment: chemotherapy
Interventions	drug = Epoetin alpha dose = 150 IU/kg sc TIW hb‐target = 14‐16 g/dL planned ESA duration = during chemotherapy
Outcomes	Primary: assess possible stimulatory effects of ESA on solid tumor growth, tumor response; secondary: overall survival, Hb, transfusion, safety
Notes	study number = 73807
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	computer‐generated
Allocation concealment?	Unclear risk	description is unclear