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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

O'Shaugnessy 2005.

Methods randomized controlled trial, placebo‐controlled
Participants n = 100, breast cancer (stage I, II, IIIB); concomitant treatment: chemotherapy
Interventions drug = Epoetin alpha
dose = 40000 IU sc weekly
hb‐target = 13‐15 g/dL
planned ESA duration = during chemotherapy
Outcomes Primary: cognitive function, fatigue; secondary: QoL
Notes study number = 40730
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk computer generated
Allocation concealment? Low risk coded drug packs of identical appearance