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. 2009 Jul 8;2009(3):CD007303. doi: 10.1002/14651858.CD007303.pub2

OBE/EPO‐INT‐03.

Methods randomized controlled trial, not placebo‐controlled
Participants n = 72, multiple myeloma; concomitant treatment: chemotherapy
Interventions drug = Epoetin alpha
dose = 40000 IU sc weekly
hb‐target = 12‐13 g/dL
planned ESA duration = during chemotherapy
Outcomes Primary: Hb change; secondary: QoL, Hb response, transfusion, safety
Notes study number = 92503
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk no description
Allocation concealment? Low risk central randomization