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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Parkinsonism Relat Disord. 2020 Feb 19;72:31–36. doi: 10.1016/j.parkreldis.2020.02.008

Table 3.

Areas that significantly correlated with Clinical Assessments in the Freezers.

Behavioral
Assesment
P value
(FWE)
Cluste
r Size
Max t MNI
Coordinates
Cortical
Brodmann
Area
Left
or
Right
Description
Single Task Performance
Time Up & Go 0.008 239 4.09 −52 −10 −40 20 L Inferior temporal
0.013 224 4.40 6 22 60 6 L & R Pre-SMA (Rostral SMA)
0.032 191 5.31 −68 −38 −6 21 L Middle temporal
Time to Turn <0.000 474 4.80 −50 −6 −40 20 L Inferior temporal
0.002 293 4.98 −68 −38 −6 21 L Middle temporal
0.019 211 3.59 −50 −2 52 6 L Lateral premotor cortex
Dual Task Performance
Time Up & Go <0.001 639 5.67 −18 28 60 6 L&R Pre-SMA (Rostral SMA)
<0.001 359 4.66 −60 −10 −34 20 & 21 L Inferior temporal
0.025 196 4.13 14 −46 18 23 R Posterior cingulate
0.035 184 4.10 −66 −56 14 39 & 40 L Supramarginal gyrus
0.049 173 6.07 10 −24 76 6 R SMA (Caudal SMA)
Time to Turn <0.001 964 4.77 −10 −6 −10 N/A L Thalamus
<0.001 842 7.58 −48 −2 −40 20 L Inferior temporal
0.001 460 5.94 54 8 −22 38 R Temporal pole
0.001 449 4.08 4 −22 74 6 L&R SMA (Caudal SMA)

Areas wherein slower behavioral performance was correlated with higher functional connectivity from the PPN in Freezers. with greater functional connectivity to the PPN in Freezers relative to Non-Freezers (Family Wise Error Correction, p<.05 at cluster level; p<0.005 voxel level).