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. 2020 May 8;15(5):e0232842. doi: 10.1371/journal.pone.0232842

Table 1. Clinical characteristics of all patients with nonsurgical hypoparathyroidism from 2005 through 2015 (n = 897).

Variable Number (% or range)a
Female sex 529 (59%)
Age at baseline, years, mean (SD) 43.8 (21.9)
Diagnosis (code), n (%)
    DiGeorge syndrome (D82.1) 36 (4.0%)
    Autoimmune polyglandular failure (E31.0) 1 (0.1%)
    Idiopathic or unspecified hypoparathyroidism (E20.0, E20.8, E20.9) 860 (95.9%)
Medication, median dose (min-max)
    Vitamin D analogs, μg/day
        Calcitriol only (n = 482) 0.25 (0.25–1.0)
        Alfacalcidol only (n = 259) 0.5 (0.5–2.0)
        Calcifediol only (n = 6) 20 (20–20)
        Mixed (n = 150) NE
    Calcium supplements
        Elemental dose, mg/day 207 (100–1487)
Complications at baseline, n (%) 393 (43.8%)
    Cardiovascular disease 139 (15.5%)
    Renal stones 9 (1.0%)
    Seizures 148 (16.5%)
    Cataract 100 (11.2%)
    Depression and bipolar disease 125 (13.9%)
    Fracture 25 (2.8%)
    Intracranial calcification 4 (0.5%)

NE, not evaluable.