Table 1. Clinical characteristics of all patients with nonsurgical hypoparathyroidism from 2005 through 2015 (n = 897).
Variable | Number (% or range)a |
---|---|
Female sex | 529 (59%) |
Age at baseline, years, mean (SD) | 43.8 (21.9) |
Diagnosis (code), n (%) | |
DiGeorge syndrome (D82.1) | 36 (4.0%) |
Autoimmune polyglandular failure (E31.0) | 1 (0.1%) |
Idiopathic or unspecified hypoparathyroidism (E20.0, E20.8, E20.9) | 860 (95.9%) |
Medication, median dose (min-max) | |
Vitamin D analogs, μg/day | |
Calcitriol only (n = 482) | 0.25 (0.25–1.0) |
Alfacalcidol only (n = 259) | 0.5 (0.5–2.0) |
Calcifediol only (n = 6) | 20 (20–20) |
Mixed (n = 150) | NE |
Calcium supplements | |
Elemental dose, mg/day | 207 (100–1487) |
Complications at baseline, n (%) | 393 (43.8%) |
Cardiovascular disease | 139 (15.5%) |
Renal stones | 9 (1.0%) |
Seizures | 148 (16.5%) |
Cataract | 100 (11.2%) |
Depression and bipolar disease | 125 (13.9%) |
Fracture | 25 (2.8%) |
Intracranial calcification | 4 (0.5%) |
NE, not evaluable.