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. 2020 Apr 13;14(4):e0008148. doi: 10.1371/journal.pntd.0008148

Table 1. Clinical data and sequencing results of each patient.

A total of 23 echinococcosis patients were involved in the study. Plasma samples were performed with ELISA tests and cell-free DNA sequencing. Lesion samples from surgery patients were performed with PCR tests.

Patient characteristics Diagnosis characteristics Cell-free DNA sequencing
ID Gender Age (Year) Clinical Typea Lesion samples (PCR) Plasma samples (ELISA) Raw Data (PE)b Clean Data (PE)b Echinococcus Reads (PE)b Echinococcus RPMc Echinococcus species
S1 Male 34 CL E. multilocularis positive 742,927,842 615,603,566 11140 18.096 E. multilocularis
S2 Female 61 CE3 E. granulosus positive 281,355,103 246,691,600 2 0.008 E. granulosus
S3 Female 30 CE1, CE4 E. granulosus positive 250,618,825 227,517,883 3 0.013 E. granulosus
S4 Male 30 CE3 E. granulosus positive 280,431,941 249,457,697 17 0.068 E. granulosus
S5 Male 40 CE3 E. granulosus positive 279,312,347 248,762,189 1 0.004 E. granulosus
S6 Female 29 CE1 E. granulosus positive 308,530,827 274,958,461 4 0.015 E. granulosus
S7 Female 44 CE2 E. granulosus positive 263,251,023 236,679,083 2 0.008 E. granulosus
S8 Male 29 CE2 E. granulosus positive 360,137,779 313,971,836 17 0.054 E. granulosus
S9 Male 15 CL E. granulosus negative 351,412,640 320,738,789 37 0.115 E. granulosus
S10 Female 30 CE2 E. granulosus positive 306,363,351 269,830,299 13 0.048 E. granulosus
S11 Female 43 CL E. granulosus positive 262,203,537 231,673,428 173 0.747 E. granulosus
S12 Female 10 CL E. granulosus positive 231,127,477 205,492,100 1 0.005 E. granulosus
S13 Female 58 CE3 E. granulosus positive 245,838,225 219,082,144 15 0.068 E. granulosus
S14 Female 36 CE1 E. granulosus negative 256,759,640 224,126,469 13 0.058 E. granulosus
N1 Female 46 CE1, CE4 NA positive 244,658,087 205,140,224 116 0.565 E. granulosus
N2 Female 59 CE2 NA positive 364,203,245 281,310,703 129 0.459 E. granulosus
N3 Male 35 CE2, CE4 NA positive 289,831,896 171,116,167 367 2.145 E. granulosus
N4 Male 58 CE5 NA negative 367,706,652 213,450,366 540 2.530 E. granulosus
N5 Male 14 CE5 NA positive 248,171,648 203,853,580 125 0.613 E. granulosus
N6 Male 47 CE5 NA negative 211,410,500 153,887,667 234 1.521 E. granulosus
N7 Male 27 CE1 NA negative 132,535,233 114,252,814 15 0.131 E. granulosus
N8 Female 49 CE2 NA positive 117,991,568 104,563,714 10 0.096 E. granulosus
N9 Female 41 CE4 NA negative 83,740,668 73,423,055 18 0.245 E. granulosus

a Clinical Type: CL, Cystic lesion. CE1-5, Cystic echinococcosis clinical stage.

b PE: Paired-end Reads.

c RPM: Read-Pairs Per Million.