Table 1. Clinical data and sequencing results of each patient.
Patient characteristics | Diagnosis characteristics | Cell-free DNA sequencing | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
ID | Gender | Age (Year) | Clinical Typea | Lesion samples (PCR) | Plasma samples (ELISA) | Raw Data (PE)b | Clean Data (PE)b | Echinococcus Reads (PE)b | Echinococcus RPMc | Echinococcus species |
S1 | Male | 34 | CL | E. multilocularis | positive | 742,927,842 | 615,603,566 | 11140 | 18.096 | E. multilocularis |
S2 | Female | 61 | CE3 | E. granulosus | positive | 281,355,103 | 246,691,600 | 2 | 0.008 | E. granulosus |
S3 | Female | 30 | CE1, CE4 | E. granulosus | positive | 250,618,825 | 227,517,883 | 3 | 0.013 | E. granulosus |
S4 | Male | 30 | CE3 | E. granulosus | positive | 280,431,941 | 249,457,697 | 17 | 0.068 | E. granulosus |
S5 | Male | 40 | CE3 | E. granulosus | positive | 279,312,347 | 248,762,189 | 1 | 0.004 | E. granulosus |
S6 | Female | 29 | CE1 | E. granulosus | positive | 308,530,827 | 274,958,461 | 4 | 0.015 | E. granulosus |
S7 | Female | 44 | CE2 | E. granulosus | positive | 263,251,023 | 236,679,083 | 2 | 0.008 | E. granulosus |
S8 | Male | 29 | CE2 | E. granulosus | positive | 360,137,779 | 313,971,836 | 17 | 0.054 | E. granulosus |
S9 | Male | 15 | CL | E. granulosus | negative | 351,412,640 | 320,738,789 | 37 | 0.115 | E. granulosus |
S10 | Female | 30 | CE2 | E. granulosus | positive | 306,363,351 | 269,830,299 | 13 | 0.048 | E. granulosus |
S11 | Female | 43 | CL | E. granulosus | positive | 262,203,537 | 231,673,428 | 173 | 0.747 | E. granulosus |
S12 | Female | 10 | CL | E. granulosus | positive | 231,127,477 | 205,492,100 | 1 | 0.005 | E. granulosus |
S13 | Female | 58 | CE3 | E. granulosus | positive | 245,838,225 | 219,082,144 | 15 | 0.068 | E. granulosus |
S14 | Female | 36 | CE1 | E. granulosus | negative | 256,759,640 | 224,126,469 | 13 | 0.058 | E. granulosus |
N1 | Female | 46 | CE1, CE4 | NA | positive | 244,658,087 | 205,140,224 | 116 | 0.565 | E. granulosus |
N2 | Female | 59 | CE2 | NA | positive | 364,203,245 | 281,310,703 | 129 | 0.459 | E. granulosus |
N3 | Male | 35 | CE2, CE4 | NA | positive | 289,831,896 | 171,116,167 | 367 | 2.145 | E. granulosus |
N4 | Male | 58 | CE5 | NA | negative | 367,706,652 | 213,450,366 | 540 | 2.530 | E. granulosus |
N5 | Male | 14 | CE5 | NA | positive | 248,171,648 | 203,853,580 | 125 | 0.613 | E. granulosus |
N6 | Male | 47 | CE5 | NA | negative | 211,410,500 | 153,887,667 | 234 | 1.521 | E. granulosus |
N7 | Male | 27 | CE1 | NA | negative | 132,535,233 | 114,252,814 | 15 | 0.131 | E. granulosus |
N8 | Female | 49 | CE2 | NA | positive | 117,991,568 | 104,563,714 | 10 | 0.096 | E. granulosus |
N9 | Female | 41 | CE4 | NA | negative | 83,740,668 | 73,423,055 | 18 | 0.245 | E. granulosus |
a Clinical Type: CL, Cystic lesion. CE1-5, Cystic echinococcosis clinical stage.
b PE: Paired-end Reads.
c RPM: Read-Pairs Per Million.