Diagnosis |
• Metastatic bone disease as most common in adults |
• Discusses difference in benign versus malignant lesions |
• Discusses different diagnoses based on age |
• Discuses different tools for diagnosis (Radiograph, CT, MRI, bone scan, and biopsy) |
Anatomy |
• Discusses most common bones affected (distal femur, proximal tibia, and proximal humerus) |
• Discusses regions of the bone affected (intramedullary, cortical, metaphyseal, and epiphyseal) |
• Sarcomas can be aggressive and extend out of the bone |
Treatment |
• Treatment may involve chemotherapy |
• Treatment may involve radiation therapy |
• Treatment may involve surgery |
• Treatment may be observation |
• Surgery has two main purposes: tumor resection and reconstruction |
• Sometimes treatment may be palliative instead of curative |
• Patients may need stabilization if at risk for pathologic fracture |
• Discusses surgical adjuvants (argon beam, phenol, and liquid nitrogen) |
• Surgery may be initially delayed and patient restaged after neoadjuvant therapy |
• Discusses limb salvage surgery versus amputation |
• Notes treatment is multidisciplinary (medical oncologist, orthopaedic oncologist, radiation oncologist, musculoskeletal radiologist, musculoskeletal pathologist, physical medicine and rehabilitation, and pain specialist) |
Complications |
• Sarcoma can metastasize to other locations (commonly lungs/other bones) |
• Lesions in weight-bearing bones may result in pathologic fractures |
• Lesions may recur even if resected |
• Patients must be monitored regularly after resection |
• Surgery in children may result in growth disturbances/limb length inequality |
• Wounds may become infected |
• Surgery may require resection of structures such as muscles, vessels, and nerves that limit future function |
Score _______/25 |