Figure 2.

Conditioned pain modulation (CPM) and offset analgesia (OA) at all measurement time points. Offset analgesia response expressed as the difference between offset trial (OT%) and constant trial (CT%) (for OT% and CT%: difference of the maximum pain ratings for T2 (T2max) and minimum pain ratings for T3 (T3min) corrected by T2max ([(T2max − T3min)/T2max] × 100%). CPM response expressed as the difference of the first test stimuli (before the conditioning stimulus) and second test stimulus and divided by first test stimulus ([(TSpost − TSpre)/TSpre] × 100%). OA response at the forearm (A) and the lower back (B), CPM response at the forearm (C) and the lower back (D). Data are presented as mean values and SEs (SEM).