Figure 1.
Genome-wide transcriptomic analysis of genes regulated by antimycin A (AA) and doxycycline (Dox). (a) Venn diagrams showing common sets of genes downregulated (down) or upregulated (up) in seedlings treated with AA for 6 h, Dox for 12 h. Numbers in parentheses correspond to the number of genes expected to overlap by chance. (*p < 6.05 × 10−23) denotes statistically significant overlap between tested sets. (b) Heatmap demonstrating gene cluster analysis of genome-wide analysis for genes induced (blue) and repressed (green) at least twofold by AA or Dox in WT. (c) Enrichment score plots analysed by GSEA using RNA sequencing data of WT plants treated with Dox (left). The list of ANAC017-dependent retrograde signalling genes was defined in Methods and was used as the gene set of interest.