Table 2. Genes involved in one-carbon metabolism identified through Gene Ontology (GO) by genetic validation.

HGNC. symbol	Fold Change	Cellular Location
ALDH1L1	4.8561047775901	cytoplasm
SHMT2	–1.0479550141666	mitochondria
MTHFD2	–1.57882401191097	mitochondria
TYMS	–2.14173789433925	cytoplasm
GLDC	–3.13552794835523	mitochondria